Getting IN on Viral RNA Condensation and Virion Maturation
نویسنده
چکیده
The retroviral enzyme integrase plays an essential role in the virus replication cycle by catalyzing the covalent insertion of newly synthesized viral DNA into the host cell chromosome early after infection. Now, Kessl et al. report a second function of integrase: binding to the viral RNA genome in virion particles late in the virus replication cycle to promote particle maturation.
منابع مشابه
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ورودعنوان ژورنال:
- Cell
دوره 166 شماره
صفحات -
تاریخ انتشار 2016